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Centrifugation technologies for continuous production processes were developed. Data of successful proof of concept tests using a batch process were used for an initial design of the process units. Based on the definition of the process performance in batch processes, the design of a centrifuge for continuous production were elaborated.

The centrifuge accomplished allows unrestricted industrial scale up and is compliant with GMP regulations, enabling even Clean in Place for pharmaceutical production.

The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European
Union’s Seventh Framework Programme FP7 (2007–2013) under REA grant agreement no. 324275 (project acronym Decent AID)